However, paucity of information regarding the protective role of Hsp70 on PQ-induced PD like symptoms led us to hypothesize that modulation of hsp70 expression in the dopaminergic neurons would improve the health of these cells. Hsp70, a molecular chaperone by function, has been shown as one of the modulators of neurological disorders. A number of epidemiological as well as case-control studies have revealed an association between pesticide exposure, especially of paraquat (PQ) and occurrence of PD. Parkinson's disease (PD) is one of the most common neurodegenerative disorders with limited clinical interventions.
